No vaccine is required for Tanzania. There’s one conditional exception, yellow fever, and it depends on the countries you pass through rather than on Tanzania itself.
Everything else is a recommendation, which means it’s a conversation with your doctor rather than a checklist you can tick off a website.
What follows is what the two public health services most travelers rely on say, and how far ahead you need to act.
Required Vaccines
That exception has a shape worth knowing.
A yellow fever certificate becomes mandatory if you arrive from a country on Tanzania’s list, or if you spend 12 hours or more in transit in one of them. Arrive straight from a country off the list and nobody asks you for anything.
That rule has its own article, because the detail matters and gets misread: which countries count, what a layover counts as, what happens if you land without the certificate. It’s all in my article on the yellow fever certificate.
Strongly Recommended Travel Vaccines
The CDC and the UK’s National Travel Health Network don’t publish the same list, and they don’t sort it the same way. Neither is wrong. They weigh the same evidence for different populations, so seeing both is more useful than seeing an average of the two.
| Vaccine | CDC | NaTHNaC |
|---|---|---|
| Hepatitis A | recommended for unvaccinated travelers aged 1 and over | most travelers |
| Typhoid | recommended for most travelers | most travelers |
| Tetanus | part of routine cover | most travelers |
| Hepatitis B | recommended for unvaccinated travelers under 60 | some travelers |
| Rabies | case by case, and note that rabies vaccine is mostly available only in larger suburban or urban medical facilities | some travelers |
| Cholera | may be considered for areas with active transmission | some travelers |
| Measles, MMR | complete cover at least 2 weeks before departure | some travelers |
| Polio | a single lifetime adult booster, since poliovirus has been identified in Tanzania in the past year | some travelers |
| Tuberculosis, BCG | not listed for travelers | some travelers |
| Chikungunya | not listed for Tanzania | some travelers |
| Dengue | not listed for Tanzania | some travelers |
Before the appointment
Three things sit around that table rather than inside it, and all three change what you walk out of the clinic with.
- What you already have. Routine cover carries most of the weight: MMR, DTaP or Td, polio, influenza, chickenpox, shingles and COVID-19, at whatever the schedule is where you live. Bring the record with you, because a missing childhood dose is easier to fix 6 weeks out than 6 days out.
- When to go. Four to six weeks before departure, and at least a month. Several of these vaccines come in more than one dose, and a yellow fever certificate only becomes valid 10 days after the injection. Leave it to the last two weeks and you’ll be paying for protection you won’t have yet.
- What’s circulating. NaTHNaC records an ongoing mpox clade I outbreak. None of this changes the table above. It changes how firmly your doctor will push the relevant lines in it.
Other Health Precautions
Two health checks run at Tanzanian entry points and neither has anything to do with your vaccination record.
- Temperature screening for mpox applies to everyone at every point of entry, and has done since March 2025.
- A heavier check applies to travelers arriving from Uganda and the Democratic Republic of the Congo, in force since May 2026.
A direct flight from Europe or North America isn’t affected by the second.
The rest of what protects you on this trip isn’t a vaccine at all, and it has its own articles:
- Malaria, which has no vaccine for travelers and is the single most important health subject for a safari: malaria in Tanzania
- The coast, where the risks are different from the parks: my guide to safety in Zanzibar
- Altitude, if Kilimanjaro is on the itinerary: my article on how altitude affects the body
- The wider picture, from road safety to what to do if something goes wrong: Tanzania safety
Read also
- Do You Need a Yellow Fever Vaccine for Tanzania?
- Climbing Kilimanjaro: How Altitude Affects the Body
- Is Zanzibar Safe? A Practical Guide for 2026
- Things to Know Before Visiting Tanzania
Last verified September 10, 2026. Recommendations and outbreak notices change, so check the sources below before you travel. Nothing here is medical advice, and the list that suits you is one only your doctor can write.
Sources
- CDC: Tanzania, including Zanzibar, traveler view
- NaTHNaC TravelHealthPro: Tanzania
- Ministry of Health, United Republic of Tanzania: Yellow Fever Entry Requirements in Tanzania Mainland, November 16, 2023
- UK FCDO: Tanzania entry requirements, updated August 31, 2026
- U.S. Embassy Dar es Salaam: health alert on mpox screening, March 14, 2025




